68Ga-DOTATATE PET/CT Can Be an Alternative Imaging Method in Insulinoma Patients

Meningiomas: A Comparative Study of 68Ga-DOTATOC, 68Ga-DOTANOC and 68Ga-DOTATATE for Molecular Imaging in Mice

PURPOSE The goal of this study was to compare the tumor uptake kinetics and diagnostic value of three (68)Ga-DOTA-labeled somatostatin analogues ((68)Ga-DOTATOC, (68)Ga-DOTANOC, and (68)Ga-DOTATATE) using PET/CT in a murine model with subcutaneous meningioma xenografts. METHODS The experiment was performed with 16 male NUDE NU/NU mice bearing xenografts of a human meningioma cell line (CH-157...

Twins in spirit - episode I: comparative preclinical evaluation of [68Ga]DOTATATE and [68Ga]HA-DOTATATE

BACKGROUND Recently, an intra-patient comparison demonstrated that the somatostatin (sst) ligand [(68)Ga]HA-DOTATATE ([(68)Ga]DOTA-3-iodo-Tyr(3)-octreotate) provides PET images comparable to or superior to those obtained with [(68)Ga]DOTATATE. To provide a comprehensive basis for nevertheless observed slight differences in tracer biodistribution and dosimetry, the characteristics of [(68)Ga]HA-...

Can Photodynamic Therapy Be an Alternative Method in Melanoma Treatment?

How can Alzheimer's Patients be Helped?

پرستاری از بیمار مبتلا به بیماری آلزایمر چندان ساده نیست. حتی اگر از این امر که اختلال رفتاری فرد نشانه ای از بیماری اوست، آگاه باشید، اکثر مواقع نمی دانید که چگونه باید با او رفتار کنید. در این مقاله روشهای مناسبی ارائه گردیده تا خانواده بیمار بتواند با ۱۰ اختلال رفتاری شایع در بیماران مبتلا بدون احساس ناامیدی و خشم سازگاری یابند. 

68Ga-DOTATATE PET/CT imaging of indeterminate pulmonary nodules and lung cancer

PURPOSE 18F-FDG PET/CT is widely used to evaluate indeterminate pulmonary nodules (IPNs). False positive results occur, especially from active granulomatous nodules. A PET-based imaging agent with superior specificity to 18F-FDG for IPNs, is badly needed, especially in areas of endemic granulomatous nodules. Somatostatin receptors (SSTR) are expressed in many malignant cells including small cel...